Review





Similar Products

fat diet  (PMI Nutrition International LLC)
94
PMI Nutrition International LLC fat diet
All C57BL/6J mice were pre-exposed to <t>the</t> <t>high-fat</t> diet for 48 hours with std. chow, and then intermittently exposed the high-fat diet (along with std. chow) for 24 hours each binge session. 1A, B) Food intake was assessed over 24 hours for both male (n=10) and female (n=10) mice for the day prior (chow only) to a binge session and then a 24-hour binge session (chow with the high-fat diet). Males and females displayed binge-like feeding behavior with highly significant increases in total kcal/g BW consumed during binge sessions compared to the chow-only consumption. C) A 2-hour timepoint (to match food intake measurements after treatments) revealed significant binge-like behavior compared to a chow-only session for males and females. D-G) No effect of DORA-22 (100 mg/kg) was observed on binge-like feeding at the 2- or 24-hour timepoints for both sexes (n= 9 males, 10 females). All error bars are S.E.M.
Fat Diet, supplied by PMI Nutrition International LLC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/western+diet/AIN-93G+Western+Diet+for+Rodents+5TJN/bio_rxiv__64898__2026__04__24__720455-64-1-8
Average 94 stars, based on 1 article reviews
fat diet - by Bioz Stars, 2026-09
94/100 stars
  Buy from Supplier
diet  (PMI Nutrition International LLC)
93
PMI Nutrition International LLC diet
All C57BL/6J mice were pre-exposed to <t>the</t> <t>high-fat</t> diet for 48 hours with std. chow, and then intermittently exposed the high-fat diet (along with std. chow) for 24 hours each binge session. 1A, B) Food intake was assessed over 24 hours for both male (n=10) and female (n=10) mice for the day prior (chow only) to a binge session and then a 24-hour binge session (chow with the high-fat diet). Males and females displayed binge-like feeding behavior with highly significant increases in total kcal/g BW consumed during binge sessions compared to the chow-only consumption. C) A 2-hour timepoint (to match food intake measurements after treatments) revealed significant binge-like behavior compared to a chow-only session for males and females. D-G) No effect of DORA-22 (100 mg/kg) was observed on binge-like feeding at the 2- or 24-hour timepoints for both sexes (n= 9 males, 10 females). All error bars are S.E.M.
Diet, supplied by PMI Nutrition International LLC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/western+diet/Breslow+Western+Diet+5TFH/pm41863601-54-13-21
Average 93 stars, based on 1 article reviews
diet - by Bioz Stars, 2026-09
93/100 stars
  Buy from Supplier
western diet  (PMI Nutrition International LLC)
93
PMI Nutrition International LLC western diet
All C57BL/6J mice were pre-exposed to <t>the</t> <t>high-fat</t> diet for 48 hours with std. chow, and then intermittently exposed the high-fat diet (along with std. chow) for 24 hours each binge session. 1A, B) Food intake was assessed over 24 hours for both male (n=10) and female (n=10) mice for the day prior (chow only) to a binge session and then a 24-hour binge session (chow with the high-fat diet). Males and females displayed binge-like feeding behavior with highly significant increases in total kcal/g BW consumed during binge sessions compared to the chow-only consumption. C) A 2-hour timepoint (to match food intake measurements after treatments) revealed significant binge-like behavior compared to a chow-only session for males and females. D-G) No effect of DORA-22 (100 mg/kg) was observed on binge-like feeding at the 2- or 24-hour timepoints for both sexes (n= 9 males, 10 females). All error bars are S.E.M.
Western Diet, supplied by PMI Nutrition International LLC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/western+diet/Breslow+Western+Diet+5TFH/pm41863601-55-4-13
Average 93 stars, based on 1 article reviews
western diet - by Bioz Stars, 2026-09
93/100 stars
  Buy from Supplier
fat  (PMI Nutrition International LLC)
94
PMI Nutrition International LLC fat
All C57BL/6J mice were pre-exposed to <t>the</t> <t>high-fat</t> diet for 48 hours with std. chow, and then intermittently exposed the high-fat diet (along with std. chow) for 24 hours each binge session. 1A, B) Food intake was assessed over 24 hours for both male (n=10) and female (n=10) mice for the day prior (chow only) to a binge session and then a 24-hour binge session (chow with the high-fat diet). Males and females displayed binge-like feeding behavior with highly significant increases in total kcal/g BW consumed during binge sessions compared to the chow-only consumption. C) A 2-hour timepoint (to match food intake measurements after treatments) revealed significant binge-like behavior compared to a chow-only session for males and females. D-G) No effect of DORA-22 (100 mg/kg) was observed on binge-like feeding at the 2- or 24-hour timepoints for both sexes (n= 9 males, 10 females). All error bars are S.E.M.
Fat, supplied by PMI Nutrition International LLC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/western+diet/AIN-93G+High+Cholesterol+(1%25)+Western+Diet+5TJT/pm41469877-59-22-26
Average 94 stars, based on 1 article reviews
fat - by Bioz Stars, 2026-09
94/100 stars
  Buy from Supplier
ain 76a western diet  (PMI Nutrition International LLC)
95
PMI Nutrition International LLC ain 76a western diet
All C57BL/6J mice were pre-exposed to <t>the</t> <t>high-fat</t> diet for 48 hours with std. chow, and then intermittently exposed the high-fat diet (along with std. chow) for 24 hours each binge session. 1A, B) Food intake was assessed over 24 hours for both male (n=10) and female (n=10) mice for the day prior (chow only) to a binge session and then a 24-hour binge session (chow with the high-fat diet). Males and females displayed binge-like feeding behavior with highly significant increases in total kcal/g BW consumed during binge sessions compared to the chow-only consumption. C) A 2-hour timepoint (to match food intake measurements after treatments) revealed significant binge-like behavior compared to a chow-only session for males and females. D-G) No effect of DORA-22 (100 mg/kg) was observed on binge-like feeding at the 2- or 24-hour timepoints for both sexes (n= 9 males, 10 females). All error bars are S.E.M.
Ain 76a Western Diet, supplied by PMI Nutrition International LLC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/western+diet/AIN-76A+Western+Diet+5342/pmc12630366-294-15-18
Average 95 stars, based on 1 article reviews
ain 76a western diet - by Bioz Stars, 2026-09
95/100 stars
  Buy from Supplier
76a western diet  (PMI Nutrition International LLC)
95
PMI Nutrition International LLC 76a western diet
All C57BL/6J mice were pre-exposed to <t>the</t> <t>high-fat</t> diet for 48 hours with std. chow, and then intermittently exposed the high-fat diet (along with std. chow) for 24 hours each binge session. 1A, B) Food intake was assessed over 24 hours for both male (n=10) and female (n=10) mice for the day prior (chow only) to a binge session and then a 24-hour binge session (chow with the high-fat diet). Males and females displayed binge-like feeding behavior with highly significant increases in total kcal/g BW consumed during binge sessions compared to the chow-only consumption. C) A 2-hour timepoint (to match food intake measurements after treatments) revealed significant binge-like behavior compared to a chow-only session for males and females. D-G) No effect of DORA-22 (100 mg/kg) was observed on binge-like feeding at the 2- or 24-hour timepoints for both sexes (n= 9 males, 10 females). All error bars are S.E.M.
76a Western Diet, supplied by PMI Nutrition International LLC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/western+diet/AIN-76A+Western+Diet+5342/pm41398033-306-11-14
Average 95 stars, based on 1 article reviews
76a western diet - by Bioz Stars, 2026-09
95/100 stars
  Buy from Supplier
milk fat  (PMI Nutrition International LLC)
95
PMI Nutrition International LLC milk fat
All C57BL/6J mice were pre-exposed to <t>the</t> <t>high-fat</t> diet for 48 hours with std. chow, and then intermittently exposed the high-fat diet (along with std. chow) for 24 hours each binge session. 1A, B) Food intake was assessed over 24 hours for both male (n=10) and female (n=10) mice for the day prior (chow only) to a binge session and then a 24-hour binge session (chow with the high-fat diet). Males and females displayed binge-like feeding behavior with highly significant increases in total kcal/g BW consumed during binge sessions compared to the chow-only consumption. C) A 2-hour timepoint (to match food intake measurements after treatments) revealed significant binge-like behavior compared to a chow-only session for males and females. D-G) No effect of DORA-22 (100 mg/kg) was observed on binge-like feeding at the 2- or 24-hour timepoints for both sexes (n= 9 males, 10 females). All error bars are S.E.M.
Milk Fat, supplied by PMI Nutrition International LLC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/western+diet/AIN-76A+Western+Diet+5342/pmc12675283-262-34-43
Average 95 stars, based on 1 article reviews
milk fat - by Bioz Stars, 2026-09
95/100 stars
  Buy from Supplier
western style fast food diet  (PMI Nutrition International LLC)
95
PMI Nutrition International LLC western style fast food diet
All C57BL/6J mice were pre-exposed to <t>the</t> <t>high-fat</t> diet for 48 hours with std. chow, and then intermittently exposed the high-fat diet (along with std. chow) for 24 hours each binge session. 1A, B) Food intake was assessed over 24 hours for both male (n=10) and female (n=10) mice for the day prior (chow only) to a binge session and then a 24-hour binge session (chow with the high-fat diet). Males and females displayed binge-like feeding behavior with highly significant increases in total kcal/g BW consumed during binge sessions compared to the chow-only consumption. C) A 2-hour timepoint (to match food intake measurements after treatments) revealed significant binge-like behavior compared to a chow-only session for males and females. D-G) No effect of DORA-22 (100 mg/kg) was observed on binge-like feeding at the 2- or 24-hour timepoints for both sexes (n= 9 males, 10 females). All error bars are S.E.M.
Western Style Fast Food Diet, supplied by PMI Nutrition International LLC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/western+diet/AIN-76A+Western+Diet+5342/pmc12643026-39-10-20
Average 95 stars, based on 1 article reviews
western style fast food diet - by Bioz Stars, 2026-09
95/100 stars
  Buy from Supplier

Image Search Results


All C57BL/6J mice were pre-exposed to the high-fat diet for 48 hours with std. chow, and then intermittently exposed the high-fat diet (along with std. chow) for 24 hours each binge session. 1A, B) Food intake was assessed over 24 hours for both male (n=10) and female (n=10) mice for the day prior (chow only) to a binge session and then a 24-hour binge session (chow with the high-fat diet). Males and females displayed binge-like feeding behavior with highly significant increases in total kcal/g BW consumed during binge sessions compared to the chow-only consumption. C) A 2-hour timepoint (to match food intake measurements after treatments) revealed significant binge-like behavior compared to a chow-only session for males and females. D-G) No effect of DORA-22 (100 mg/kg) was observed on binge-like feeding at the 2- or 24-hour timepoints for both sexes (n= 9 males, 10 females). All error bars are S.E.M.

Journal: bioRxiv

Article Title: The selective OX1R antagonist 1-SORA-51 reduces binge-like feeding behavior in male and female mice without detectable changes in dopamine

doi: 10.64898/2026.04.24.720455

Figure Lengend Snippet: All C57BL/6J mice were pre-exposed to the high-fat diet for 48 hours with std. chow, and then intermittently exposed the high-fat diet (along with std. chow) for 24 hours each binge session. 1A, B) Food intake was assessed over 24 hours for both male (n=10) and female (n=10) mice for the day prior (chow only) to a binge session and then a 24-hour binge session (chow with the high-fat diet). Males and females displayed binge-like feeding behavior with highly significant increases in total kcal/g BW consumed during binge sessions compared to the chow-only consumption. C) A 2-hour timepoint (to match food intake measurements after treatments) revealed significant binge-like behavior compared to a chow-only session for males and females. D-G) No effect of DORA-22 (100 mg/kg) was observed on binge-like feeding at the 2- or 24-hour timepoints for both sexes (n= 9 males, 10 females). All error bars are S.E.M.

Article Snippet: The high-fat diet used for all studies (5TJN, TestDiet, Richmond, Indiana) provides 4.55 kcal/g with the following caloric breakdown: protein 15.8%, fat 39.1%, and carbohydrates 45.1%.

Techniques:

All C57BL/6J mice were pre-exposed to the high-fat diet for 48 hours with std. chow, and then intermittently exposed the high-fat diet (along with std. chow) for 24 hours each binge session. A) A significant reduction in binge-like feeding was observed at the 2-hour timepoint for male mice treated with 1-SORA-51 (100 mg/kg) compared to vehicle treatment sessions (vehicle n=10, 1-SORA-51 n=8). B) The effect of 1-SORA-51 did not last across the 24-hour period. C) Similarly, a significant reduction in binge-like feeding was observed at the 2-hour timepoint for female mice treated with 1-SORA-51 (100 mg/kg) compared to vehicle treatment sessions (vehicle n=8, 1-SORA-51 n=9). D) The effect of 1-SORA-51 did not last across the 24-hour period. All error bars are S.E.M.

Journal: bioRxiv

Article Title: The selective OX1R antagonist 1-SORA-51 reduces binge-like feeding behavior in male and female mice without detectable changes in dopamine

doi: 10.64898/2026.04.24.720455

Figure Lengend Snippet: All C57BL/6J mice were pre-exposed to the high-fat diet for 48 hours with std. chow, and then intermittently exposed the high-fat diet (along with std. chow) for 24 hours each binge session. A) A significant reduction in binge-like feeding was observed at the 2-hour timepoint for male mice treated with 1-SORA-51 (100 mg/kg) compared to vehicle treatment sessions (vehicle n=10, 1-SORA-51 n=8). B) The effect of 1-SORA-51 did not last across the 24-hour period. C) Similarly, a significant reduction in binge-like feeding was observed at the 2-hour timepoint for female mice treated with 1-SORA-51 (100 mg/kg) compared to vehicle treatment sessions (vehicle n=8, 1-SORA-51 n=9). D) The effect of 1-SORA-51 did not last across the 24-hour period. All error bars are S.E.M.

Article Snippet: The high-fat diet used for all studies (5TJN, TestDiet, Richmond, Indiana) provides 4.55 kcal/g with the following caloric breakdown: protein 15.8%, fat 39.1%, and carbohydrates 45.1%.

Techniques:

A) Male and female mice (n=9) expressing the GRABDA 2m sensor and finished binge training underwent fiber photometry sessions, during which baseline was recorded prior to treatment via gavage, and then provided access to the high-fat diet for 2 hours. Shown here is fluorescence normalized to baseline. No effect of treatment was seen during the 30 minutes after gavage or after HF pellet delivery. B) Treatment with 1-SORA-51 resulted in significantly less high-fat pellet consumption compared to vehicle sessions. All error bars are S.E.M.

Journal: bioRxiv

Article Title: The selective OX1R antagonist 1-SORA-51 reduces binge-like feeding behavior in male and female mice without detectable changes in dopamine

doi: 10.64898/2026.04.24.720455

Figure Lengend Snippet: A) Male and female mice (n=9) expressing the GRABDA 2m sensor and finished binge training underwent fiber photometry sessions, during which baseline was recorded prior to treatment via gavage, and then provided access to the high-fat diet for 2 hours. Shown here is fluorescence normalized to baseline. No effect of treatment was seen during the 30 minutes after gavage or after HF pellet delivery. B) Treatment with 1-SORA-51 resulted in significantly less high-fat pellet consumption compared to vehicle sessions. All error bars are S.E.M.

Article Snippet: The high-fat diet used for all studies (5TJN, TestDiet, Richmond, Indiana) provides 4.55 kcal/g with the following caloric breakdown: protein 15.8%, fat 39.1%, and carbohydrates 45.1%.

Techniques: Expressing, Fluorescence